Three countries have big games on display Friday, headlined by the second leg of the Coppa Italia between Juventus and AC Milan.
The tie is level at one from the first leg in Milan, where Ante Rebic and Cristiano Ronaldo traded goals.
The winner of the 3 p.m. ET kickoff will meet the winner of Napoli and Inter Milan, who play their second leg on Saturday.
[ MORE: New PL schedule ]
Over in Germany, USMNT mainstay Tyler Adams begins on the bench when Leipzig heads to Hoffenheim with a view to clamping down on a top four spot.
Hoffenheim has caretaker boss Marcel Rapp looking over his first match as the hosts aim for better Europa League footing in a 2:30 p.m. ET kickoff.
Finally there’s a La Liga doubleheader, with Grenada and Getafe beginning things at 1:30 p.m. ET before Valencia and Levante tangle at 4 p.m. ET.
All four teams harbor hopes of either the Champions League or Europa League, so stakes are high in Spain.
How to Watch Hoffenheim v. RB Leipzig
When: 2:30 p.m. ET Friday
TV Channel: FS2
Stream Live: Via Fox Soccer
USMNT players in action: Tyler Adams
How to watch Juventus v. AC Milan
TV Channels: N/A
Stream Live: ESPN+
When: 3 p.m. ET Friday
La Liga schedule, how to watch Friday
TV Channels: beIN Sports USA
Stream Live: Via beinSports
When: 1:30 p.m. ET (Grenada v. Getafe)
4 p.m. ET (Valencia v. Levante)